The Medical Research Institute was established to contribute to the advancement of medicine and promotion of health by performing investigations in medical and its related areas. Its main operational goals are;

Academic studies in medicine and related fields
Facilitation of research communication
Information service on research
Publishing services including periodicals
Rendering various academic forums such as academic and research seminars, and
medical educational meetings for the general public.

Samsung Biomedical Research Institute

The Samsung Biomedical Research Institute (SBRI) was established in 1995 by the physicians, basic scientists and biomedical engineers of the Samsung Medical Group. The institute's vision is to contribute to the advancement of medical services and human welfare through the integration of medical science and modern technology. In addition, the institute aims to provide new business areas of bio-pharmaceutical and bioengineering in the 21st century through research and development of life science and medical technology. The institute is roughly divided into 2 fields: Center for Molecular Research and Center for Clinical Research.
The Center for Molecular Research, headed by Professor Jung Don Seo now has four main laboratories, Nucleic Acid Biochemistry Laboratory, Molecular Immunology Laboratory, Molecular Virology Laboratory, and Molecular Genetics Laboratory. The Center for Clinical Research directed by Professor Jong Chul Rhee has four major parts, Clinical Research Laboratory, Clinical Pharmacology Laboratory, Experimental Animal Facility, and Biomedical Statistics. The Clinical Research Laboratory has various study groups for Cancer Research, Cardiovascular Research, Metabolic Research, Genetic Disease Research, Gastrointestinal Research, Musculoskeletal System Research, Infectious Disease Research, and Transplantation Research.
SBRI is engaged in various dynamic research projects and the many publications are proof of hard and creative works.

Laboratory Animal Research Center (LARC) & Facility for Genetically Engineered Mice (FGEM)

The Laboratory Animal Research Center (LARC) is one of the key components of Sungkyunkwan University School of Medicine (SKKUSM), and is responsible for all animal care and use at its site. In addition to the animal care needs of SKKUSM including Basic Medicine, Clinical Medicine, and the Center for Molecular Research of Samsung Biomedical Research Institute (SBRI), the LARC supports the laboratory animal care needs of other Samsung Medical Center (SMC) research groups and investigators.
The SKKUSM's facility is situated in an environmentally controlled building. The building is dedicated to biomedical studies using rats, mice, hamsters, guinea pigs, gerbils, rabbits, pigs and dogs. The first underground floor of the building is dedicated to the FGEM which houses breeding colonies of genetically engineered mice and also assigned for laboratories for genetic engineering, embryo manipulation, gamma-irradiator room, administration office and other supporting facilities. The second underground floor is assigned to housing rats, mice, hamsters, guinea-pigs, gerbils, rabbits, pigs and dogs as well as laboratories for laboratory animal medicine, office rooms and some supporting facilities. This floor also has a Biosafety Level 3 Infection animal room and its supporting facilities.
The animal research facility in the first underground floor of the LARC facility is about 13,916 ft2 (1,296 m2). The conventional animal area for rabbits, dogs and pigs is about 794 ft2 (73 m2). The Semi-clean area for rats and mice is about 995 ft2 (96 m2) while the barrier-sustained area for mice and rats is about 2,177 ft2 (207 m2).
There are a surgical suite for aseptic surgery, a necropsy room, a gamma-irradiator room, a Biological Safety Level 3 infection room, a refrigerated food and bedding storage room, and a freezing carcass storage room. The animal research facility is routinely accessed via the security checkup that limits access. Traffic into and out of the facility is always monitored through a Computer system and CCD cameras.
Currently, FGEM is capable of producing approximately 50 trangenic mice per year and carries more than 50 founder mice of 20 trangenic mouse lines as well as 16 different knockout mice each in 2 or 3 different genetic backgrounds.